Opto-acoustic effect of Au nanoparticles in water under irradiation of pulse laser
Opto-acoustic effect of Au nanoparticles in water under irradiation of pulse laser
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DOI：
10.1016/j.ijleo.2019.163512
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发表时间：
2020-02-01
期刊：
影响因子：
3.1
通讯作者：
Sun, Mingjian
中科院分区：
文献类型：
--
作者：
Gao, Renxi;Fu, Rongpeng;Sun, Mingjian
激光辐照的金纳米粒子在水中产生的空化泡在光热治疗和增强光声成像方面具有潜在的应用前景。对相关过程的探索对于提高光声效率是至关重要的，而光声效率对这些应用非常重要。建立了包括Mie理论、气体状态方程、Rayleigh-Plesset方程和声压方程的模型。通过该模型，得到了Au纳米粒子的最佳直径、激光诱导空化的阈值、气泡的体积和压力随时间的变化。在此模型的基础上，模拟了激光流量和纳米粒子直径对气泡体积和压力的影响。多个Au Np的声压是通过单个Au Np的光声波叠加得到的，其中Au Np在激光照射区域内随机分布。实验研究了多个Au纳米粒子的光声波，与理论分析相吻合。
The cavitation bubbles in water generated by laser irradiated Au nanoparticles (NPs) exhibit potential applications in the photothermal therapy and enhancing photoacoustic imaging. The exploration of the related processes is crucial to improve the opto-acoustic efficiency that is important to these applications. Herein a model including the Mie theory, gas state equation, Rayleigh-Plesset equation, and sound pressure equation is established. Through this model, the optimal diameter of an Au NP, the threshold value of the laser induced cavitation, the time varying volume and pressure of the bubble is obtained. The influences of laser flux and NP diameter to the volume and pressure of the bubble are simulated based on this model. The acoustic pressure of many Au NPs is obtained through the superposition of the opto-acoustic wave of a single Au NP, in which the Au NPs are assumed to be distributed randomly in the laser irradiation area. The opto-acoustic wave of many Au NPs is also investigated experimentally, which coincides with the theoretical analyses.