Ion Peak Narrowing by Applying Additional AC Voltage (Ripple Voltage) to FAIMS Extractor Electrode
Ion Peak Narrowing by Applying Additional AC Voltage (Ripple Voltage) to FAIMS Extractor Electrode
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DOI：
10.1016/j.jasms.2009.09.001
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发表时间：
2010-01-01
影响因子：
3.2
通讯作者：
Sheven, Dmitriy G.
中科院分区：
文献类型：
--
作者：
Pervukhin, Viktor V.;Sheven, Dmitriy G.
在高场非对称波形离子迁移谱(FAIMS)分析仪中使用非均匀电场提高了灵敏度，但降低了分辨率。在萃取器电极上施加一个额外的交流电压(“纹波”电压，U(纹波))可以克服这种影响，从而减小FAIMS的峰宽。在这种方法中，在器件圆柱形部分的非均匀电场中，扩散离子损失保持在最小，而在紫外光下的所有离子损失都发生在其路径的一小部分。在萃取器电极上施加纹波电压的效率是沿器件总长度施加U(纹波)的两倍。(J am Soc MS Spectrm 2010，21，47-52)(C)2010美国质谱学学会
The use of a non-uniform electric field in a high-field asymmetric waveform ion mobility spectrometry (FAIMS) analyzer increases sensitivity but decreases resolution. The application of an additional AC voltage to the extractor electrode ("ripple" voltage, U(ripple)) can overcome this effect, which decreases the FAIMS peak width. In this approach, the diffusion ion loss remains minimal in the non-uniform electric field in the cylindrical part of the device, and all ion losses under Uripple occur in a short portion of their path. Application of the ripple voltage to the extractor electrode is twice as efficient as the applying of U(ripple) along the total length of the device. (J Am Soc Mass Spectrom 2010, 21, 47-52) (C) 2010 American Society for Mass Spectrometry