Role of acid and duodenogastroesophageal reflux in gastroesophageal reflux disease
Role of acid and duodenogastroesophageal reflux in gastroesophageal reflux disease
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DOI：
10.1053/gast.1996.v111.pm8898632
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发表时间：
1996-11-01
期刊：
影响因子：
29.4
通讯作者：
Richter, JE
中科院分区：
文献类型：
--
作者：
Vaezi, MF;Richter, JE
Background & Aims: Acid and pepsin are known to cause esophagitis. However, the role of duodenogastroesophageal reflux (DGER) in producing esophageal mucosal injury across the spectrum of gastroesophageal reflux disease (GERD) is controversial. Methods: Twenty controls (13 men; mean age, 41 years), 30 patients with GERD (15 men; mean age, 41 years), and 20 patients with Barrett's esophagus (17 men; mean age, 58 years) were studied. Twenty-four-hour ambulatory acid and bilirubin measurements were obtained with Bilitec 2000 using a glass pH electrode and fiberoptic sensor. Results: Percentage times pH was
