Neural response to fast food commercials in adolescents predicts intake
Neural response to fast food commercials in adolescents predicts intake
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DOI：
10.1093/ajcn/nqz305
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发表时间：
2020-03-01
影响因子：
7.1
通讯作者：
Lumeng, Julie C.
中科院分区：
文献类型：
--
作者：
Gearhardt, Ashley N.;Yokum, Sonja;Lumeng, Julie C.
背景：食品广告是肥胖的主要原因，快餐店是最大的广告商。关于食品广告对青少年的影响的研究是缺乏的，以前的研究也没有调查过青少年食物摄入的神经预测因素。涉及奖励的神经系统可能是理解食品广告如何驱动food intake.Objectives：To investigate how neural responses to both unhealthy and healthy FF commercials predict food intake in adolescents.Methods：A cross-sectional sampling of 171 adolescents（aged 1316 y）who ranged from normal weight to obesity completed an fMRI paradigm where they viewed unhealthy and healthy FF and nonfood commercials.青少年，然后在一个模拟的FF餐厅，不同的营养配置文件（不健康与健康相比）的食品available.Results：奖励相关区域（核尾状核，r = 0.29，r = 0.27）更大的神经激活不健康的FF广告预测更大的总食物摄入量。在与奖励相关的地区，相对于非食品广告，对更健康的FF的反应更大（即，丘脑核，r = 0.24），记忆（即，海马，r = 0.32），和感觉运动过程（即，小脑前区（r = 0.33）预测了更大的食物总量和更不健康的食物摄入量，但没有预测更健康的食物摄入量。与视觉注意力和显著性相关的神经区域的激活较低（例如，楔前叶，r = -0.35）不健康相对于健康的FF广告预测健康的食物摄入。结论：这些研究结果表明，FF广告有助于通过奖励机制在青少年暴饮暴食。增加FF餐厅的健康广告不太可能鼓励更健康的食物摄入，但降低不健康FF广告吸引注意力的能力的干预措施可能是有益的。然而，总体上减少青少年接触FF商业广告的数量可能是最有效的方法。
Background: Food advertising is a major contributor to obesity, and fast food (FF) restaurants are top advertisers. Research on the impact of food advertising in adolescents is lacking and no prior research has investigated neural predictors of food intake in adolescents. Neural systems implicated in reward could be key to understanding how food advertising drives food intake.Objectives: To investigate how neural responses to both unhealthy and healthier FF commercials predict food intake in adolescents.Methods: A cross-sectional sample of 171 adolescents (aged 1316 y) who ranged from normal weight to obese completed an fMRI paradigm where they viewed unhealthy and healthier FF and nonfood commercials. Adolescents then consumed a meal in a simulated FF restaurant where foods of varying nutritional profiles (unhealthy compared with healthier) were available.Results: Greater neural activation in reward-related regions (nucleus accumbens, r = 0.29; caudate nucleus, r = 0.27) to unhealthy FF commercials predicted greater total food intake. Greater responses to healthier FF relative to nonfood commercials in regions associated with reward (i.e., nucleus accumbens, r = 0.24), memory (i.e., hippocampus, r = 0.32), and sensorimotor processes (i.e., anterior cerebellum, r = 0.33) predicted greater total food and unhealthier food intake, but not healthier food intake. Lower activation in neural regions associated with visual attention and salience (e.g., precuneus, r = -0.35) to unhealthy relative to healthier FF commercials predicted healthier food intake.Conclusions: These findings suggest that FF commercials contribute to overeating in adolescents through reward mechanisms. The addition of healthier commercials from FF restaurants is unlikely to encourage healthier food intake, but interventions that reduce the ability of unhealthy FF commercials to capture attention could be beneficial. However, an overall reduction in the amount of FF commercials exposure for adolescents is likely to be the most effective approach.