RELATIONS BETWEEN STRUCTURE AND FUNCTION IN DESIGN OF SKELETAL MUSCLES
RELATIONS BETWEEN STRUCTURE AND FUNCTION IN DESIGN OF SKELETAL MUSCLES
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DOI：
10.1152/jn.1965.28.3.581
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发表时间：
1965-01-01
影响因子：
2.5
通讯作者：
OLSON, CB
中科院分区：
文献类型：
--
作者：
HENNEMAN, E;OLSON, CB
比目鱼肌和比目鱼肌的组织化学研究。腓肠肌使用最近开发的用于ATP酶的肌纤维染色方法制备猫的肌肉。线粒体内存在三种不同大小和ATP酶含量的纤维。G.其中只有一种，B型，大小和反应性中等，被发现在比目鱼肌。测定每种纤维的数量、直径和总横截面积，并观察梭内纤维的纺锤体。组织化学的结果提供了一个详细的功能分析的背景，以前的数据在这些相同的肌肉运动单位。关于运动神经元和运动单位的大小、阈值和“使用”的假设，从这一分析中出现，为组织学发现提供了理论依据。这些不同的观察结果，都与相同的肌肉有关，使作者能够指出一些以前没有认识到的原则，支配骨骼肌的设计。
A histochemical study of the soleus and m. gastro-cnemius (M.G.) muscles of the cat was made, using recently developed methods of staining muscle fibers for ATPase. Three types of fibers differing in size and mitochondrial ATPase content were identified in M. G. Only one of these, type B, intermediate in size and reactivity, was found in soleus. The numbers, diameters and total cross-sectional areas of each type of fiber were determined and observations were made on the intrafusal fibers in their spindles. The histochemical findings provide a background for a detailed functional anaylsis of prior data on motor units in these same muscles. Hypotheses concerning the size, threshold and "usage" of motor neurons and motor units, which emerge from this analysis, offer a rationale for the histological findings. The conjunction of these different observations, all concerned with the same muscles, permits the authors to point out some previously unrecognized principles which govern the design of skeletal muscle.