Hair cell regeneration: an exciting phenomenon...but will restoring hearing and balance be possible?

Hair cell regeneration: an exciting phenomenon...but will restoring hearing and balance be possible?
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DOI:
10.1682/jrrd.2005.01.0008
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发表时间:
2005-07
影响因子:
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通讯作者:
Jonathan I. Matsui;B. Ryals
Jonathan I. Matsui;B. Ryals
中科院分区:
--
文献类型:
--
作者:
Jonathan I. Matsui;B. Ryals

文献摘要

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Sensory hair cells of the inner ear are susceptible to damage from a variety of sources including aging, genetic defects, and environmental stresses such as loud noises or chemotherapeutic drugs. Unfortunately, the consequence of this damage in humans is often permanent hearing/balance problems. The discovery that hair cells can regenerate in birds and other nonmammalian vertebrates has fueled a wide range of studies that are designed to find ways of restoring hearing and balance after such damage. In this review, we will discuss some of the key recent findings in sensory hair cell regeneration and what they mean for audiologists and other hearing healthcare practitioners.