Biomimetic Models for the Active Site of [Fe]Hydrogenase Featuring an Acylmethyl(hydroxymethyl)pyridine Ligand
Biomimetic Models for the Active Site of [Fe]Hydrogenase Featuring an Acylmethyl(hydroxymethyl)pyridine Ligand
复制标题
以酰甲基（羟甲基）吡啶配体为特征的[Fe]氢化酶活性位点的仿生模型
DOI：
10.1021/ic301146u
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发表时间：
2012-07-16
影响因子：
4.6
通讯作者：
Song, Hai-Bin
中科院分区：
文献类型：
--
作者：
Song, Li-Cheng;Xie, Zhao-Jun;Song, Hai-Bin
以2-（4-MeC_6H_4SO_3CH_2）-6-HOCH_2C_5H_3N与Na_2Fe（CO）（4）的亲核取代反应为起始反应，合成了第一个含酰基甲基（羟甲基）吡啶配体的[Fe]氢化酶模型配合物2-4。通过原位红外光谱监测了通过高度不稳定的中间体络合物1制备络合物3的反应过程，同时对分离的模型络合物2-4进行了充分表征。
The first acylmethyl(hydroxymethyl)pyridine ligand-containing [Fe]hydrogenase model complexes 2-4 have been synthesized starting from the nucleophilic substitution reaction of 2-(4-MeC6H4SO3CH2)-6-HOCH2C5H3N with Na2Fe(CO)(4). While the reaction course for producing complex 3 via the highly unstable intermediate complex 1 is monitored by in situ IR spectroscopy, the isolated model complexes 2-4 are fully characterized.