Synthesis and characterisation of O-6-alkylthio- and perfluoroalkylpropanethio-α-cyclodextrins and their O-2-, O-3-methylated analogues
Synthesis and characterisation of O-6-alkylthio- and perfluoroalkylpropanethio-α-cyclodextrins and their O-2-, O-3-methylated analogues
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DOI：
10.1039/b703894a
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发表时间：
2007-01-01
影响因子：
3.3
通讯作者：
Parrot-Lopez, Hélène
中科院分区：
文献类型：
--
作者：
Ghera, Bernard Bertino;Perret, Florent;Parrot-Lopez, Hélène
十二烷硫基-或-过氧化氢的合成。描述了氟烷基丙硫基-α-环糊精衍生物及其O-2-，O-3-甲基化类似物。偶联反应首先涉及烷基全氟丙烷异硫脲鎓碘化物或烷基异硫脲鎓溴化物的碱性原位水解，然后与在C-6位被碘或甲磺酰基修饰的α-环糊精反应。这些新化合物的界面性质已确定其在空气-水界面的单分子层的研究。
The synthesis of twelve alkylthio- or per. uoroalkylpropanethio-alpha-cyclodextrin derivatives and their O-2-, O-3-methylated analogues are described. The coupling reaction involves firstly the basic in situ hydrolysis of alkylperfluoropropane isothiouronium iodide or alkylisothiouronium bromide, then reaction with an alpha-cyclodextrin modified at the C-6 position by an iodine or methylsulfonyl group. The interfacial properties of these new compounds have been determined by the studies of their mono-molecular layer at the air-water interface.