Magnetomechanics of superparamagnetic beads on a magnetic merry-go-round: from micromagnetics to radial looping

Magnetomechanics of superparamagnetic beads on a magnetic merry-go-round: from micromagnetics to radial looping
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磁性旋转木马上超顺磁珠的磁力学:从微磁学到径向循环

DOI:
10.1088/1361-6463/aa5cef
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发表时间:
2017
期刊:
Journal of Physics D: Applied Physics
影响因子:
--
通讯作者:
J. McCord
J. McCord
中科院分区:
--
文献类型:
--
作者:
U. Sajjad;R.B. Holländer;F. Klingbeil;J. McCord

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功能化的超顺磁珠的运动为在微流体环境中操纵标记的化学和生物物种提供了基础,其中图案化的铁磁薄膜为生物医学应用提供了一个多功能和可重构的平台。通过移动由软磁盘的循环微磁状态产生的杂散磁场梯度来实现超顺磁性微珠的重复释放和捕获。输运动力学的完整微磁分析充分描述了微球运动的基本交替行为。对于所有运动阶段,实验和模拟之间获得了很好的一致性,证实了在应用的准从头模拟方法中描述粒子运动动力学的有效性。对非线性微珠位移的理解为各种替代动态激励方案的建模开辟了道路,甚至对于复杂的集成微磁平台,用于受控的生物分析物-超顺磁珠操纵。
The motion of functionalized superparamagnetic beads provides the foundation for the manipulation of labelled chemical and biological species in microfluidic environments, where patterned ferromagnetic thin films serve as a versatile and reconfigurable platform for biomedical applications. A recurring release and capture of superparamagnetic microbeads is achieved by moving stray magnetic field gradients generated by a circulating micromagnetic state of a soft magnetic disc. The full micromagnetic analysis of the transport dynamics fully describes the fundamental alternating behaviour of microsphere motion. An excellent level of agreement is obtained between experiment and modelling for all stages of motion, confirming the validity of describing particle motion dynamics in the applied quasi ab initio modelling approach. The demonstrated comprehension of the non-linear microbead displacement opens the way towards the modelling of various alternative dynamic excitation schemes, even for complicated integrated micromagnetic platforms, for controlled biological analyte–superparamagnetic bead manipulation.
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