Neuropsychiatric Aspects of Tuberous Sclerosis
Neuropsychiatric Aspects of Tuberous Sclerosis
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结节性硬化症的神经精神方面
DOI：
10.1111/j.1749-6632.1991.tb37743.x
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发表时间：
1991
影响因子：
5.2
通讯作者：
O. Dulac
中科院分区：
文献类型：
--
作者：
P. Curatolo;R. Cusmai;F. Cortesi;C. Chiron;I. Jambaqué;O. Dulac
评估了 34 名结节性硬化症 (TSC) 儿童（年龄 5 个月至 18 岁）的癫痫自然史、神经心理学特征以及脑电图病灶定位和磁共振成像 (MRI) 病变之间的可能关系。结果表明，只有考虑到许多变量（例如皮质结节的解剖定位、癫痫类型和症状出现年龄）的清晰而全面的方法，才能更好地了解学习和行为障碍。人们还认为，TSC 的神经和精神结果可能在很大程度上与皮质结节的解剖定位有关。因此，通过 MRI 进行早期检测可能对新诊断病例具有很大的预后价值。（PsycINFO 数据库记录 (c) 2016 APA，保留所有权利）
Evaluated the possible relation between the natural history of epilepsy, the neuropsychologic features, and the localization of EEG foci and magnetic resonance imaging (MRI) lesions in 34 children (aged 5 mo to 18 yrs) with tuberous sclerosis (TSC). Results indicate that only an articulate and comprehensive approach that takes into account a number of variables, such as the anatomic localization of cortical tubers, the type of epilepsy, and the age at onset of symptoms, can provide a better understanding of learning and behavioral impairment. It is also thought that neurologic and psychiatric outcome in TSC may be related, to a great extent, to the anatomic localization of cortical tubers; therefore, their early detection by MRI may be of great prognostic value mainly in newly diagnosed cases.(PsycINFO Database Record (c) 2016 APA, all rights reserved)