Cells know how big they are

Cells know how big they are
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DOI:
10.1016/j.molp.2021.06.019
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发表时间:
2021
期刊:
影响因子:
27.5
通讯作者:
Du Fei
Du Fei
中科院分区:
生物学1区
文献类型:
--
作者:
Du Fei

文献摘要

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In eukaryotic organisms,cell sizes are normally maintained at a stable level specific to species and cell types.However,the original sizes of two daughter cells are not always equal right after mitosis.In the Arabidopsis shoot apical meristem,besides symmetric division,asymmetric division generates a large daughter cell and a small daughter cell.If these two daughter cells go through the progression of a cell cycle within the same time course,one would expect an enhanced variability of cell sizes throughout the meristem.In fact,the cell size variability is corrected by adjusting different growth periods before the large and small daughter cell divide.How cells sense their own sizes and control the progression through cell cycles remains unclear.