Radiographic findings in cats with mycobacterial infections
Radiographic findings in cats with mycobacterial infections
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DOI：
10.1016/j.jfms.2011.06.006
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发表时间：
2011-10-01
影响因子：
1.7
通讯作者：
Gunn-Moore, Danielle A.
中科院分区：
文献类型：
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作者：
Bennett, Alexander D.;Lalor, Stephanie;Gunn-Moore, Danielle A.
这项研究描述了 33 只家猫中与分枝杆菌感染相关的放射线变化，这些变化经培养或干扰素-γ 测试证实。感染最常见于成年猫（平均年龄 5.7 岁；范围 1.5-12 岁）、非纯种猫（87%；27/31）、绝育公猫（69%；22/32）。最常见的感染是田鼠分枝杆菌（60%；18/30）和牛分枝杆菌（37%；11/30）；鸟分枝杆菌和马尔默分枝杆菌很少被培养（各 3%；1/30）。提供胸部（24 只猫）、腹部（8 只）、附肢骨骼（11 只）和头部（3 只）的 X 光片。放射学变化最常见地影响胸部，包括支气管（46%；11/24）、肺泡（38%；9/24）、结节性非结构性间质性（38%；9/24）或非结构性间质性（25%；6/24）肺模式，这些模式通常是混合的。肺门周围或胸骨淋巴结肿大很常见（42%；10/24），特别是肺门周围淋巴结肿大（25%；6/24）。骨骼变化见于远端前臂（3处）、足部（2处）、上颌骨、肩胛骨、脊柱、臂骨、股骨和跗骨（各1处）。变化通常是溶骨性的（73%；8/11），通常是渗透性溶骨性的（64%；7/11）。三只猫出现骨质增生变化，五只猫出现软组织肿胀，四只猫出现骨异常。其他变化包括颌下软组织肿胀，主动脉、主动脉根部和头臂干明显钙化，前臂远端软组织肿胀伴钙化，但不累及骨。腹部变化并不常见（见于 2/8 的猫），包括肝肿大和肝脾肿大。总之，放射学变化多种多样，没有病变可诊断分枝杆菌感染，病理最常见于胸部。 (C) 2011 ISFM 和 AAFP。由爱思唯尔有限公司出版。保留所有权利。
This study describes radiographic changes associated with mycobacterial infection in 33 domestic cats confirmed by culture or interferon-gamma testing. Infection was seen most frequently in adult (average age 5.7 years; range 1.5-12 years), non-pedigree (87%; 27/31), neutered male cats (69%; 22/32). The most common infections were Mycobacterium microti (60%; 18/30) and Mycobacterium bovis (37%; 11/30); Mycobacterium avium and Mycobacterium malmoense were infrequently cultured (3% of each; 1/30). Radiographs were available for the thorax (24 cats), abdomen (eight), appendicular skeleton (11) and head (three). Radiographic changes affected the thorax most commonly, consisting of bronchial (46%; 11/24), alveolar (38%; 9/24), nodular unstructured interstitial (38%; 9/24) or unstructured interstitial (25%; 6/24) lung patterns, which were often mixed. Perihilar or sternal lymphadenopathy were common (42%; 10/24), particularly perihilar lymphadenopathy (25%; 6/24). Skeletal changes were found in the distal antebrachium (three), pes (two), maxilla, scapula, spine, manus, femur, and tarsus (one each). Changes were typically osteolytic (73%; 8/11), often permeative osteolytic (64%; 7/11). Osteoproliferative changes were seen in three cats and soft tissue swelling in five cats, which were adjacent to the bony abnormality in four cats. Other changes included submandibular soft tissue swelling, marked aortic, aortic root and brachiocephalic trunk calcification, and soft tissue swelling with calcification in the distal antebranchium which was not involving bone. Abdominal changes were uncommon (seen in 2/8 cats) and consisted of hepatomegaly and hepatosplenomegaly. In summary, radiographic changes were varied, no lesion was pathognomic for mycobacterial infection, and pathology was seen most commonly in the thorax. (C) 2011 ISFM and AAFP. Published by Elsevier Ltd. All rights reserved.