[Vitamin and mineral status in chronic renal failure--the effect of protein restriction].
[Vitamin and mineral status in chronic renal failure--the effect of protein restriction].
复制标题
[慢性肾功能衰竭中的维生素和矿物质状态——蛋白质限制的影响]。
DOI：
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发表时间：
1994
期刊：
影响因子：
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通讯作者：
T. Satoh
中科院分区：
文献类型：
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作者：
M. Hida;H. Fujii;T. Satoh
慢性肾功能衰竭（CRF）患者存在必需氨基酸（EAA）、维生素和矿物质异常。我们认为改变饮食限制是导致这些异常的众多因素之一。测定不同程度CRF门诊人群（血清肌酐3.6 ~ 6.8mg/dl）低蛋白饮食中的EAA、维生素和矿物质含量以及血液中的维生素和矿物质含量。实验结果如下：1。20克蛋白质/天的日粮可提供足量的氨基酸。2. 低蛋白质日粮（30克蛋白质/天）缺乏维生素A、B1、B2和B6。饲粮中维生素A、B1、B2和B6分别为日最低需用量的70-80%、40-50%、30-35%和20-25%。3. 低蛋白质日粮（30g蛋白质/d日粮）钙、铁和锌含量不足。这些日粮的钙和铁含量分别为最低日需氧量的30%和50%。在富含植物蛋白的饮食中，尽管蛋白质含量很低（植物：动物= 2:1），但锌含量约为每日最低需要量的55%。4. 约21.4%的CRF患者血浆维生素B1水平较低。约28.6%和33.3%的CRF患者血浆维生素B2和B6水平较低。这些患者的血浆叶酸水平并不不足。5. 约28.6%、50%和35.7%的CRF患者血浆Ca、Fe和Zn水平较低。综上所述，蛋白质限制性CRF患者应考虑补充维生素B1、B2、B6、Ca、Fe和Zn。
Essential amino acid (EAA), vitamin and mineral abnormalities are found in patients with chronic renal failure (CRF). We considered altered dietary restriction to be one of many factors that can promote these abnormalities. We determined the EAA, vitamin and mineral content of low-protein diets and vitamins and minerals in the blood of outpatient populations with various degrees of CRF (serum creatinine 3.6-6.8mg/dl). The results obtained were as follows: 1. 20g-protein/day diet can provide an adequate amount of EAA. 2. Low protein diets (30g protein/day diets) were inadequate in vitamins A, B1, B2 and B6. Vitamins A, B1, B2 and B6 in these diets were 70-80%, 40-50%, 30-35% and 20-25% of the minimum daily requirements, respectively. 3. Low protein diets (30g protein/day diets) were inadequate in Ca, Fe and Zn. The Ca and Fe contents of these diets were 30% and 50% of the minimum daily requirements, respectively. The Zn content of a diet rich in vegetable protein, although low in protein, overall (vegetable: animal = 2:1), was about 55% of the minimum daily requirement. 4. About 21.4% of the CRF patients had low levels of plasma vitamins B1. About 28.6% and 33.3% of the CRF patients had low levels of plasma vitamins B2 and B6, respectively. Plasma folic acid levels were not inadequate in these patients. 5. About 28.6%, 50% and 35.7% of the CRF patients had low levels of plasma Ca, Fe and Zn, respectively. In conclusion, it seems that supplementation of vitamins B1, B2, B6, Ca, Fe and Zn should be considered for protein-restricted CRF patients.