The effects of locomotor activity on gastrointestinal symptoms of irritable bowel syndrome among younger people: An observational study
The effects of locomotor activity on gastrointestinal symptoms of irritable bowel syndrome among younger people: An observational study
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DOI：
10.1371/journal.pone.0234089
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发表时间：
2020-05-29
期刊：
影响因子：
3.7
通讯作者：
Fukudo, Shin
中科院分区：
文献类型：
--
作者：
Hamaguchi, Toyohiro;Tayama, Jun;Fukudo, Shin
肠易激综合征（IBS）是一种常见的肠道疾病，表现为不明原因的腹痛或不适以及腹泻、便秘或两者交替模式形式的排便习惯改变。一些证据表明，增加体力活动可以改善IBS症状。因此，建议这些患者每天进行锻炼。在这项研究中，我们的目的是调查101名大学生（女= 78）IBS的体力活动和胃肠道症状的关系。采用胃肠道症状评定量表（GSRS）对受试者进行检查，并使用计步器测量1周的步态步数。GSRS评分和计步器计数之间的关联通过有序逻辑模型分析确定。GSRS和自发活动的有序逻辑回归模型显示出显著的逐步拟合（z =-3.05，p = 0.002）。逻辑曲线将GSRS评分从5分（中度严重不适）和2分（轻微不适）的自发活动分开。每日自发活动区分GSRS的5和4点的概率（即，可能具有逆转症状）的概率随着每天步数的增加而降低：4000步的概率为78%，6000步的概率为70%，8000步的概率为59%，10000步的概率为48%。这项研究表明，GSRS的严重程度与年轻IBS患者的步行量有关。这些结果可以作为一种措施，以确定每日步数，以减少胃肠道症状的严重程度与IBS的个人。
Irritable bowel syndrome (IBS) is a common bowel disorder that manifests as unexplained abdominal pain or discomfort and bowel habit changes in the form of diarrhea, constipation, or alternating patterns of the two. Some evidences demonstrate that increased physical activity improves IBS symptoms. Hence, daily exercise is recommended in these patients. In this study, we aimed to investigate the relationship between physical activity and gastrointestinal symptoms in 101 university students (female = 78) with IBS. Participants were examined by Gastrointestinal Symptoms Rating Scale (GSRS), and gait steps were measured for 1 week using a pedometer. The association between the GSRS score and pedometer counts was determined by ordinal logistic modeling analysis. The ordinal logistic regression model for GSRS and locomotor activity showed a significant stepwise fit (z = -3.05, p = 0.002). The logistic curve separated GSRS score of 5 points (moderately severe discomfort) from 2 points (minor discomfort) by locomotor activity. The probability for daily locomotor activity to discriminate between 5 and 4 points of GSRS (i.e., likely to have reverse symptoms) decreased in accordance with increment of steps per day: 78% probability for 4000 steps, 70% probability for 6000 steps, 59% probability for 8000 steps, and 48% probability for 10000 steps. This study demonstrated that the severity of GSRS is associated with the amount of walking in younger people with IBS. These results may be used as a measure to determine the daily step count to reduce the severity of gastrointestinal symptoms in individuals with IBS.