C-reactive protein concentration distribution among US children and young adults: Findings from the National Health and Nutrition Examination Survey, 1999-2000

C-reactive protein concentration distribution among US children and young adults: Findings from the National Health and Nutrition Examination Survey, 1999-2000
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DOI:
10.1373/49.8.1353
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发表时间:
2003-08-01
期刊:
影响因子:
9.3
通讯作者:
Mannino, DM
Mannino, DM
中科院分区:
医学1区
文献类型:
--
作者:
Ford, ES;Giles, WH;Mannino, DM

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背景资料:C反应蛋白(CRP)浓度在美国儿童和年轻人中的分布目前尚不清楚。方法:我们使用了3348名美国儿童和3-19岁的年轻人的数据,他们参加了1999-2000年的国家健康和营养检查调查,以描述CRP浓度的分布,结果:CRP浓度范围为0.1- 90.8mg/L,平均值为1.6mg/L,几何平均值为0.5mg/L,中位数为0.4mg/L。CRP浓度随年龄增长而增加。16-19岁女性的浓度高于该年龄范围内的男性(P = 0.003)。在三个主要种族或民族中,墨西哥裔美国人的CRP浓度最高(P
Background: The distribution of C-reactive protein (CRP) concentrations among children and young adults in the US is not known at present.Methods: We used data from 3348 US children and young adults 3-19 years of age who participated in the National Health and Nutrition Examination Survey, 1999-2000, to describe the distribution of CRP concentrations, based on results obtained with a high-sensitivity latex-enhanced turbidimetric assay.Results: The range of CRP concentrations was 0.1-90.8 mg/L (mean, 1.6 mg/L; geometric mean, 0.5 mg/L; median, 0.4 mg/L). CRP concentrations increased with age. Females 16-19 years of age had higher concentrations than males in this age range (P = 0.003). Mexican Americans had the highest CRP concentrations among the three major race or ethnic groups (P