Metabolomics analysis of blood identifies potential biomarkers and possible treatment targets for nocturia
Metabolomics analysis of blood identifies potential biomarkers and possible treatment targets for nocturia
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DOI：
10.1177/1756287219850087
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发表时间：
2019-05-01
影响因子：
2
通讯作者：
Takeda, Masayuki
中科院分区：
文献类型：
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作者：
Kira, Satoru;Mitsui, Takahiko;Takeda, Masayuki
背景：我们的目的是研究血清代谢物与夜尿症之间的关系。方法：选取66例65 ~ 80岁男性，按排尿行为进行分层，采用连续3天的24 h频率容积图（FVC）、国际前列腺症状评分（IPSS）、生活质量评分。夜尿症组包括任何总IPSS的参与者，平均3晚排尿次数为1.5次/夜，而对照组包括总IPSS < 8和8次/夜的参与者
Background: Our aim was to investigate the association between serum metabolites and nocturia. Methods: A total of 66 males aged 65-80 years were enrolled in this study and stratified according to micturition behavior, which was characterized in terms of the 24 h frequency volume chart (FVC) for 3 consecutive days, the International Prostate Symptom Score (IPSS), and quality-of-life score. The nocturia group included participants with any total IPSS and > 1.5 micturitions/night as the mean of 3 nights, while the control group included participants with total IPSS < 8 and