A novel extraction method of fetal electrocardiogram from the composite abdominal signal
A novel extraction method of fetal electrocardiogram from the composite abdominal signal
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DOI：
10.1109/tbme.2006.883791
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发表时间：
2007-01-01
影响因子：
4.6
通讯作者：
Nakao, Mitsuyuki
中科院分区：
文献类型：
--
作者：
Sato, Michiyoshi;Kimura, Yoshitaka;Nakao, Mitsuyuki
与胎儿心脏运动的超声测量相反，胎儿心电图（ECG）提供关于胎儿的电生理状态的临床上重要的信息。本文提出了一种从腹部复合信号中提取胎儿心电信号的新方法。该方法包括母亲的ECG和盲源分离与参考信号（BSSR）的取消。通过减去心脏向量的相互正交投影的线性组合来消除母亲的ECG分量。BSSR是一种定点算法，其拉格朗日函数包括提取信号和参考信号之间的高阶互相关作为成本项而不是约束。这以简单的形式实现了拉格朗日函数的凸性，保证了算法的收敛性。实际应用表明，该方法除能提取R波外，还能提取P波和T波。通过与第二产程直接记录的心电图进行比较，证实了该方法的可靠性和准确性。提取的胎儿心电图生理参数与心磁图生理参数的孕周相关性也很好地吻合，证明了该方法的临床适用性。
In contrast to the ultrasonic measurement of fetal heart motion, the fetal electrocardiogram (ECG) provides clinically significant information concerning the electrophysiological state of a fetus. In this paper, a novel method for extracting the fetal ECG from abdominal composite signals is proposed. This method consists of the cancellation of the mother's ECG and blind source separation with the reference signal (BSSR). The cancellation of the mother's ECG component was performed by subtracting the linear combination of mutually orthogonal projections of the heart vector. The BSSR is a fixed-point algorithm, the Lagrange function of which includes the higher order cross-correlation between the extracted signal and the reference signal as the cost term rather than a constraint. This realizes the convexity of the Lagrange function in a simple form, which guarantees the convergence of the algorithm. By practical application, the proposed method has been shown to be able to extract the P and T waves in addition to the R wave. The reliability and accuracy of the proposed method was confirmed-by comparing the extracted signals with the directly recorded ECG at the second stage of labor. The gestational age-dependency of the physiological parameters of the extracted fetal ECG also coincided well with that of the magnetocardiogram, which proves the clinical applicability of the proposed method.