Integration of Input Signals into the Gene Network in the Plant Circadian Clock
Integration of Input Signals into the Gene Network in the Plant Circadian Clock
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DOI：
10.1093/pcp/pcx066
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发表时间：
2017-06-01
影响因子：
4.9
通讯作者：
Endo, Motomu
中科院分区：
文献类型：
--
作者：
Inoue, Keisuke;Araki, Takashi;Endo, Motomu
生物钟是一种内源性的计时机制，使生物体能够预测和准备日常的环境变化，并增加其在不断变化的环境中的适应性。植物中的生物钟，就像动物和昆虫一样，由一个基因网络组成，形成多个连锁的转录反馈环。为了使内部生物节律与周围环境同步，生物钟必须通过环境线索进行精确调整。光和温度是植物生物钟的两个主要输入信号。此外，营养状况也是植物时钟的关键输入。虽然许多研究表明，这些外部信号可以通过影响几个时钟基因的转录水平来影响昼夜节律，但人们对输入信号如何整合到核心时钟振荡器中并在分子水平上重置昼夜节律知之甚少。最近，一些研究表明，每一个输入信号相互影响，并且输入信号之间存在相互作用。在这篇综述中，我们总结了最近的研究结果，输入信号之间的相互作用和输入信号的整合到植物的生物钟。
The circadian clock, an endogenous timekeeping mechanism, allows organisms to anticipate and prepare for daily environmental changes and increase their fitness in changing environments. Circadian clocks in plants, as in animals and insects, consist of a gene network forming multiple interlocking transcriptional feedback loops. To synchronize internal biological rhythms with surrounding environments, circadian clocks must be precisely adjusted by environmental cues. Light and temperature are well known as two major input signals for the plant circadian clock. In addition, it is emerging that nutritional status is also a crucial input for the plant clock. Although numerous studies have revealed that these external cues can entrain the circadian rhythms by affecting the transcript levels of several clock genes, little is known about how input signals are integrated into the core clock oscillator and reset the circadian rhythms at the molecular level. Recently, several studies have demonstrated that each of the input signals mutually influences the others, and that there are interactions among input signals. In this review, we summarize recent findings regarding the interactions among input signals and the integration of input signals into the circadian clocks in plants.