PDMS-based microfluidic devices for biomedical applications
PDMS-based microfluidic devices for biomedical applications
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DOI：
10.1016/s0167-9317(02)00494-x
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发表时间：
2002-07-01
影响因子：
2.3
通讯作者：
Fujii, T
中科院分区：
文献类型：
--
作者：
Fujii, T
微流控装置为微尺度生化系统的分析和/或合成提供了许多有利的特征。例如，PDMS（聚二甲基硅氧烷）微芯片具有用于电泳分离的微通道，可以通过成型工艺轻松制造。这些通道的密封不需要任何复杂的粘合过程，通常需要玻璃芯片。我们一直致力于基于pdm的生物医学应用微流体装置，其中微反应器，毛细管凝胶电泳微芯片和疏水排气阀已成功制造和操作。介绍了基于pdm的微流控器件的基本原理、功能及实验结果。(C) 2002 Elsevier Science B.V.版权所有
Microfluidic devices provide a number of advantageous features for microscale biochemical systems for analysis and/or synthesis. A PDMS (polydimethylsiloxane) microchip, for instance, which has microchannels for electrophoretic separation can be easily fabricated through a molding process. Sealing of those channels does not need any elaborate bonding processes which are usually required for glass chips. We have been working on PDMS-based microfluidic devices for biomedical applications, where microreactors, microchips for capillary gel electrophoresis, and hydrophobic vent valves are successfully fabricated and operated. Fundamentals of PDMS-based microfluidic devices and their functions are described as well as the experimental results. (C) 2002 Elsevier Science B.V. All rights reserved.