Use of wireless motility capsule to determine gastric emptying and small intestinal transit times in critically ill trauma patients
Use of wireless motility capsule to determine gastric emptying and small intestinal transit times in critically ill trauma patients
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DOI：
10.1016/j.jcrc.2011.12.002
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发表时间：
2012-10-01
影响因子：
3.7
通讯作者：
Sessler, Daniel I.
中科院分区：
文献类型：
--
作者：
Rauch, Stefan;Krueger, Kristine;Sessler, Daniel I.
目的：本研究的目的是使用新型无线动力胶囊来比较危重创伤患者和健康志愿者的胃排空和小肠通过时间。材料和方法：我们评估了 8 名危重创伤患者的胃排空、小肠通过时间和总肠通过时间。这些数据与另一项单独试验中 87 名健康志愿者获得的数据进行了比较。数据通过动力胶囊获得，该胶囊将 pH、压力和温度无线传输到每个受试者腹部的记录仪。结果：危重患者的胃排空时间（中位数，13.9；四分位距 [IQR]，6.6-48.3 小时）比健康志愿者（中位数，3.0；IQR，2.5-3.9 小时）显着更长，P < .001.危重患者的小肠转运时间明显长于健康志愿者（中位数为 6.7 小时；IQR，4.4-8.5 小时 vs 中位数为 3.8 小时；IQR，3.1-4.7 小时），P = 0.01。此外，重症监护组的胶囊在 10（IQR，8.5-13）天后排出，健康志愿者则在 1.2（IQR，0.9-1.9）天后排出（P < .001）。结论：危重创伤患者的胃排空和小肠转运均延迟。 (C) 2012 Elsevier Inc. 保留所有权利。
Purpose: The purpose of this study is to use a novel wireless motility capsule to compare gastric emptying and small bowel transit times in critically ill trauma patients and healthy volunteers.Materials and Methods: We evaluated gastric emptying, small bowel transit time, and total intestinal transit time in 8 critically ill trauma patients. These data were compared with those obtained in 87 healthy volunteers from a separate trial. Data were obtained with a motility capsule that wirelessly transmitted pH, pressure, and temperature to a recorder attached to each subject's abdomen.Results: The gastric emptying time was significantly longer in critically ill patients (median, 13.9; interquartile range [IQR], 6.6-48.3 hours) than in healthy volunteers (median, 3.0; IQR, 2.5-3.9 hours), P < .001. The small bowel transit time in critically ill patients was significantly longer than in healthy volunteers (median, 6.7 hours; IQR, 4.4-8.5 hours vs median, 3.8 hours; IQR, 3.1-4.7 hours), P = .01. Furthermore, the capsules passed after 10 (IQR, 8.5-13) days in the critical care group and 1.2 (IQR, 0.9-1.9) days in healthy volunteers (P < .001).Conclusions: Both gastric emptying and small bowel transit were delayed in critically ill trauma patients. (C) 2012 Elsevier Inc. All rights reserved.