Menopause-related symptoms: What are the background factors? A prospective population-based cohort study of Swedish women (The Women's Health in Lund Area study)
Menopause-related symptoms: What are the background factors? A prospective population-based cohort study of Swedish women (The Women's Health in Lund Area study)
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DOI：
10.1016/s0002-9378(03)00872-x
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发表时间：
2003-12-01
影响因子：
9.8
通讯作者：
Nerbrand, C
中科院分区：
文献类型：
--
作者：
Li, CR;Samsioe, G;Nerbrand, C
目的：本研究的目的是分析社会人口特征和环境因素对自我报告的更年期相关症状的影响中年瑞典women.Study设计：妇女谁出生在1935年至1945年，谁住在瑞典南部的隆德地区进行了调查。每位妇女完成了一份通用问卷，并进行了一次个人访谈，涉及社会人口特征，生活方式和当前的健康相关问题。与这些背景因素，潮热和阴道干燥的频率和强度进行了测定，风险因素分析进行了评估与使用的多元回归models.RESULTS：有6917名参与者，响应率为64%。较低的潮热风险与年龄较大，受教育程度高和剧烈的体育锻炼有关。血管痉挛的主要危险因素是目前的体重增加，兼职工作，卵巢切除术，不健康的生活方式，以及伴随的健康问题。轻度吸烟、绝经年龄较晚、受教育程度较高和体重过重可降低阴道干燥的风险。然而，年龄较大，婚姻和慢性疾病对阴道投诉产生负面影响。背景因素对使用激素替代therapy.CONCLUSION的妇女的症状影响较小：社会人口学特征，生活方式和伴随的健康问题似乎是绝经相关症状的重要可改变的决定因素。(Am J Obstet Gynecol 2003;189：1646-53.）
OBJECTIVE: The purpose of this study was to analyze the influence of sociodemographic characteristics and environmental factors on self-reported menopause-related symptoms among middle-aged Swedish women.STUDY DESIGN: Women who were born in the years 1935 to 1945 and who were living in the Lund area of southern Sweden were investigated. Each woman completed a generic questionnaire and underwent a personal interview that pertained to sociodemographic characteristics, lifestyle, and current health-related problems. With these background factors, the frequency and intensity of hot flushes and vaginal dryness were determined; risk factor analysis was evaluated with the use of the multiple regression models.RESULTS: There were 6917 participants, with a response rate of 64%. A lower risk for hot flushes was related to older age, high education, and vigorous physical exercise. The major risk factors for vasomotor complaints were current weight gain, part-time employment, oophorectomy, unhealthy lifestyle, and concomitant health problems. Light smoking, late age of menopause, higher education, and excessive weight reduced the risk of vaginal dryness. However, older age, marriage, and chronic diseases negatively affected vaginal complaints. The background factors had less impact on symptoms in women who used hormone replacement therapy.CONCLUSION: Sociodemographic characteristics, lifestyle, and concomitant health problems appear to be important modifiable determinants for menopause-related symptoms. (Am J Obstet Gynecol 2003;189: 1646-53.)