Chapter 1 Common Data Elements and Federal Interagency Traumatic Brain Injury Research Informatics System for TBI Research.
Chapter 1 Common Data Elements and Federal Interagency Traumatic Brain Injury Research Informatics System for TBI Research.
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DOI：
10.1891/0739-6686.33.1
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发表时间：
2015
影响因子：
--
通讯作者：
Rivara FP
中科院分区：
文献类型：
--
作者：
Thompson HJ;Vavilala MS;Rivara FP
尽管创伤性脑损伤(TBI)受到越来越多的关注，但仍然没有专门的治疗方法，可用的干预措施更多地集中在预防继发性损伤上。缺乏成功治疗的原因之一是在临床试验中将不同类型的损伤合并在同一严重类别下。信息学方法已经被建议作为一种手段来开发一种改进的TBI分类系统。作为联邦机构间努力的结果，现已开发出用于TBI的通用数据元素(CDE)。此外，联邦机构间创伤性脑损伤研究信息学系统(FITBIR)已经创建，现在可以供脑损伤研究人员添加和检索数据。本章将讨论CDE和FITBIR的目标、发展和演变，并讨论如何使用这些工具来支持TBI研究。文中包括了使用CDE的具体范例以及从CDE和FITBIR中吸取的经验教训，以帮助未来的研究人员。
Despite increased attention to traumatic brain injury (TBI), there remains no specific treatment and available interventions focus rather on the prevention of secondary injury. One of the reasons posited for the lack of a successful therapy is the amalgamation of various types of injuries under the same severity category in clinical trials. Informatics approaches have been suggested as a means to develop an improved classification system for TBI. As a result of federal interagency efforts, common data elements (CDEs) for TBI have now been developed. Further, the Federal Interagency Traumatic Brain Injury Research Informatics System (FITBIR) has been created and is now available for TBI researchers to both add and retrieve data. This chapter will discuss the goals, development, and evolution of the CDEs and FITBIR and discuss how these tools can be used to support TBI research. A specific exemplar using the CDEs and lessons learned from working with the CDEs and FITBIR are included to aid future researchers.