Diagnosing dry eye using a blue-free barrier filter
Diagnosing dry eye using a blue-free barrier filter
复制标题
DOI：
10.1016/s0002-9394(03)00317-9
复制
发表时间：
2003-09-01
影响因子：
4.2
通讯作者：
Tano, Y
中科院分区：
文献类型：
--
作者：
Koh, S;Watanabe, H;Tano, Y
。目的：探讨蓝色无障碍滤光片(BF滤光片)在干眼症诊断中的作用。设计：非随机临床对照。方法：选择干燥综合征或干燥性角结膜炎患者53只眼，共42只眼。在颞结膜和鼻结膜进行荧光素染色，染色评分(BF评分)和不加滤光片(FL评分)为0~3分。孟加拉红染色评分相同(RB评分)。结果：FL评分为0、1、2分时，BF评分分别为0.85+/-0.37(P=.031)、1.74+/-0.65(P=.001)和2.65+/-0.48(P=.001)，FL评分为3时，BF评分均为3。当FL评分为0和I时，66.6%的患者BF评分优于FL评分，当FL评分为2时，65.2%的患者BF评分优于FL评分，而当FL评分为3时，BF评分较高，分别为1.88±/-0.92、1.78+/-0.79和2.57~0.50(均P=.001)，而当FL评分为3时，BF评分为2.97+/-0.16。当RB评分为0和1时，BF评分优于RB评分的比例为75.5%；当FL评分为2时，BF评分优于RB评分的比例为57.8%，而当RB评分为3时，BF评分优于RB评分的比例为57.8%。结论：BF滤光片可检测到荧光素染色的结膜上皮损伤。在轻到中度的病例中使用过滤器是有益的，而在重度病例中则不是。BF过滤器即使在常规观察无法检测到的初始阶段也可以诊断干眼症。(C)2003，由Elsevier Inc.保留所有权利。
. PURPOSE: To investigate the benefit of the blue,free barrier filter (BF filter) in diagnosing dry eye.. DESIGN: Nonrandomized clinical comparison.. METHODS: Fifty,three eyes with Sjogren syndrome (n = 42) or keratoconjunctivitis sicca (n = 11) were enrolled. Fluorescein staining was performed in temporal and nasal conjunctiva, and staining was scored with (BF score) and without the filter (FL score) from 0 to 3. Rose bengal staining was also scored (RB score) similarly.. RESULTS: With FL scores of 0, 1, or 2, the BF score was significantly higher: 0.85 +/- 0.37 (P = .031), 1.74 +/- 0.65 (P = .001), and 2.65 +/- 0.48 (P = .001), respectively; with a FL score of 3, the BF score was 3 at all sites. The BF score was superior to the FL score in 66.6% of cases when the FL score was 0 and I and in 65.2% when the FL score was 2, but not when the FL, score was 3. When the RB score was 0, 1, or 2, the BF score was higher: 1.88 +/- 0.92, 1.78 +/- 0.79, and 2.57 - 0.50, respectively (P = .001 for all); when the RB score was 3, the BF score was 2.97 +/- 0.16. The BF score was superior to the RB score in 75.5% of cases when the RB score was 0 and 1 and in 57.8% when the FL score was 2, but not in cases with a RB score of 3.. CONCLUSIONS: The BF filter detects damaged con, junctival epithelium stained with fluorescein. Using the filter was beneficial in mild-to-moderate cases, not in severe cases. The BF filter allows diagnosis of dry eye even at the initial stage that is undetectable by conventional observation. (C) 2003 by Elsevier Inc. All rights reserved.