Cardiac Adverse Events With Remdesivir in COVID-19 Infection.

Cardiac Adverse Events With Remdesivir in COVID-19 Infection.
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Remdesivir在COVID-19感染中的心脏不良事件。

DOI:
10.7759/cureus.11132
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发表时间:
2020-10-24
期刊:
Cureus
影响因子:
--
通讯作者:
Parker J
Parker J
中科院分区:
其他
文献类型:
--
作者:
Gupta AK;Parker BM;Priyadarshi V;Parker J

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Since December 2019, coronavirus has gradually progressed to a pandemic with no efficacious treatment. Remdesivir is an antiviral medication and inhibitor of viral RNA dependent RNA polymerase with inhibitory action against SARS-CoV virus. Two patients diagnosed with coronavirus infection with worsening respiratory status were initiated with multimodality therapy with antibiotics, steroids and remdesivir. After initiation of remdesivir, the patients’ developed bradycardia, with one of the two also showing signs of worsening QT interval. This reverted upon stopping remdesvir therapy. The prevalence of bradycardia with prolonged QT interval is not well-known yet with this medication.
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