Analyzing Propensity Matched Zero-Inflated Count Outcomes in Observational Studies.
Analyzing Propensity Matched Zero-Inflated Count Outcomes in Observational Studies.
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DOI：
10.1080/02664763.2013.834296
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发表时间：
2014-01-01
影响因子：
1.5
通讯作者：
Spinale FG
中科院分区：
文献类型：
--
作者：
Desantis SM;Lazaridis C;Ji S;Spinale FG
Determining the effectiveness of different treatments from observational data, which are characterized by imbalance between groups due to lack of randomization, is challenging. Propensity matching is often used to rectify imbalances among prognostic variables. However, there are no guidelines on how appropriately to analyze group matched data when the outcome is a zero inflated count. In addition, there is debate over whether to account for correlation of responses induced by matching, and/or whether to adjust for variables used in generating the propensity score in the final analysis. The aim of this research is to compare covariate unadjusted and adjusted zero-inflated Poisson models that do and do not account for the correlation. A simulation study is conducted, demonstrating that it is necessary to adjust for potential residual confounding, but that accounting for correlation is less important. The methods are applied to a biomedical research data set.
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Austin, Peter C.
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通讯作者：
Bowers, Jake
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Austin, Peter C.
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ZEGER, SL
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ROSENBAUM, PR