Development of an active palpation sensor for detecting prostate cancer and hypertrophy
Development of an active palpation sensor for detecting prostate cancer and hypertrophy
复制标题
开发用于检测前列腺癌和肥大的主动触诊传感器
DOI：
10.1299/jsmemecjo.2002.1.0_239
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
S. Chonan
中科院分区：
文献类型：
--
作者：
Mami Tanaka;T. Adachi;Y. Tanahashi;S. Chonan
本文涉及用于检测前列腺癌和肥大的主动触诊传感器的开发。传感器的接收器是放置在海绵橡胶层表面的聚偏二氟乙烯（PVDF）薄膜。它安装在线性 z 轴平移杆上，插入受检者的直肠，同时受到医用橡胶手套的保护。面向前列腺定位后，传感器探头以约 50 Hz 的正弦曲线驱动，峰峰值幅度为 2 mm。来自 PVDF 薄膜的电压信号在采样周期内进行积分，并用作传感器的输出，以提取所收集数据的特征。传感器对27个正常和不健康前列腺的硬度评估与医生触诊的诊断结果进行比较。结果表明，传感器的输出随着前列腺硬度的增加而变大，这与医生对硬度的评价有很好的相关性。实验室测试的进一步结果再次证实本发明的传感器能够很好地在体内非侵入性地区分前列腺的硬度。
This paper is concerned with the development of an active palpation sensor for detecting prostatic cancer and hypertrophy. The receptor of the sensor is a polyvinylidene fluoride (PVDF) film placed on the surface of a sponge rubber layer. It is mounted on a linear z-translation bar and inserted into the examinee's rectum whilst being protected by a medical rubber glove. After being positioned to face the prostate gland, the sensor probe is driven sinusoidally at about 50 Hz, with a peak-to-peak amplitude of 2 mm. The voltage signal from the PVDF film is integrated over the sampling period and is used as the output of the sensor for extracting the features of the collected data. The evaluation of the stiffness by the sensor on 27 normal and unhealthy prostate glands are compared with the results of diagnosis by the doctor's palpation. It is shown that the output of the sensor becomes greater with an increase of the stiffness of the prostate gland, which has a good correlation with the doctor's evaluation on the stiffness. Further results on the laboratory test reconfirm that the present sensor well discriminates the stiffness of the prostate glands in vivo and non-invasively.