Prevention of ventricular fibrillation with magnesium sulfate.
Prevention of ventricular fibrillation with magnesium sulfate.
复制标题
用硫酸镁预防心室颤动。
DOI：
10.1016/0014-2999(88)90269-5
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发表时间：
1988
影响因子：
5
通讯作者：
Hoskins,RS
中科院分区：
文献类型：
--
作者：
Billman,GE;Hoskins,RS
杂种犬心肌梗死愈合后，在运动试验中结扎冠脉2min。运动加缺血试验在9只动物中诱发了室颤。1周后，静脉注射硫酸镁(100 mg/kg)，重复实验。镁在9只动物中有7只预防了室颤，没有不良副作用。因此，镁在治疗缺血期的室颤方面可能是有用的。
Mongrel dogs with healed myocardial infarctions were given a 2 min coronary occlusion during an exercise test. The exercise plus ischemia test induced ventricular fibrillation in nine animals. One week later, the test was repeated after pretreatment with magnesium sulfate (100 mg/kg i.v.). Magnesium prevented ventricular fibrillation in seven of the nine animals without adverse side effects. Thus, magnesium may be useful in the management of ventricular fibrillation during ischemia.