NEURONAL GROWTH, ATROPHY AND DEATH IN A SEXUALLY DIMORPHIC SONG NUCLEUS IN THE ZEBRA FINCH BRAIN
NEURONAL GROWTH, ATROPHY AND DEATH IN A SEXUALLY DIMORPHIC SONG NUCLEUS IN THE ZEBRA FINCH BRAIN
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DOI：
10.1038/315145a0
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发表时间：
1985-01-01
期刊：
影响因子：
64.8
通讯作者：
AKUTAGAWA, E
中科院分区：
文献类型：
--
作者：
KONISHI, M;AKUTAGAWA, E
雄性斑胸草雀大脑的鸣叫控制核比雌性含有更多直径更大的神经元1。这种性别二态性被认为是两性神经元生长差异的结果2-4。利用神经组织学技术和放射性示踪剂，我们研究了几个参与控制鸣叫的前脑核的发育，发现这种二态性是由女性大脑中的神经元萎缩和死亡以及男性中其他前脑核的细胞体大小和传入末梢的增加引起的。尽管这些事件的发生时间因细胞核而异，但除 X 区外，所有这些事件的顺序本质上是相似的。这里我们以这些细胞核之一（即古纹状体的鲁棒核（RA））中的事件为例进行描述。
The song control nuclei of the zebra finch brain contain more neurones of larger diameter in the male than in the female1. This sexual dimorphism is thought to result from differential growth of neurones in the two sexes2–4. Using neurohistological techniques and radioactive tracers, we have studied the development of several forebrain nuclei involved in the control of song and find that the dimorphism arises from neuronal atrophy and death in the female brain as well as from an increase in cell-body size and afferent terminals from other forebrain nuclei in the male. Although the timing of these events varies from nucleus to nucleus, the sequence is essentially similar in all of them except area X. Here we describe the events in one of these nuclei, the robust nucleus of archistriatum (RA), as an example.