Brain tumors in the elderly - Recent trends in a Minnesota cohort study
Brain tumors in the elderly - Recent trends in a Minnesota cohort study
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DOI：
10.1001/archneur.55.7.922
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发表时间：
1998-07-01
影响因子：
--
通讯作者：
Lowry, PW
中科院分区：
文献类型：
--
作者：
Lowry, JK;Snyder, JJ;Lowry, PW
目的：比较老年患者的临床表现、诊断时间和生存率设计：回顾性队列研究，背景：明尼苏达州明尼阿波利斯市的四家医院，患者：1980年至1995年期间，714名诊断为憎恨并治疗原发性恶性脑肿瘤的患者; 230例（32%）为65岁或以上。主要结果指标：分析主要症状的类型和持续时间、诊断时间、治疗方式和患者生存率。老年患者从症状发作到诊断的时间并不比年轻患者长，18至24岁的患者除外，诊断延迟时间明显延长（P = 0.004）。老年患者出现头痛或癫痫发作的可能性显著降低（P
Objective: To compare the clinical presentation, time elapsed to diagnosis, and survival of elderly patients (greater than or equal to 65 years) with that in younger patients with malignant primary brain tumors.Design: Retrospective cohort study.Setting: Four hospitals in Minneapolis, Minn.Patients: Seven hundred fourteen patients diagnosed as hating and treated for primary malignant brain tumors between 1980 and 1995; 230 (32%) were 65 years or older.Main Outcome Measures: The type and duration of the chief presenting symptom, the time elapsed to diagnosis, the treatment modalities used, and patient survival were analyzed.Results: Time elapsed from onset of symptom to diagnosis was not longer for elderly patients than younger ones, with the exception of patients aged 18 to 24 years, who had a significantly longer delay in diagnosis (P =.004). Elderly patients were significantly less likely to present with headache or seizure (P