Clinical evaluation of a PHMB-impregnated biocellulose dressing on paediatric lacerations

Clinical evaluation of a PHMB-impregnated biocellulose dressing on paediatric lacerations
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DOI:
10.12968/jowc.2011.20.6.280
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发表时间:
2011-06-01
影响因子:
1.9
通讯作者:
van Gent, M.
van Gent, M.
中科院分区:
医学4区
文献类型:
--
作者:
Alblas, J. G.;Andriessen, A.;van Gent, M.

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目的:为了评估的临床效益,主要是耐受性和减少疼痛水平,与使用的PHMB浸渍的生物合成纤维素敷料(Suprasorb X + PHMB)对儿科足跟lacerations.Method:这些撕裂伤时造成的儿童,谁被运送到他们的父母的自行车,得到他们的脚跟被困在车轮辐条。在这些损伤仅包括皮肤挫伤和撕裂伤的情况下,治疗之前包括清洁,然后应用常规敷料和湿润伤口愈合敷料。然而,高感染率需要定期更换敷料,这给父母和孩子带来了压力和焦虑。该临床评价评估了新治疗方案的受益,其中使用PHMB浸渍的生物纤维素敷料并留在原位,直到发生上皮形成。使用软木夹板3天,以防止马蹄足,并让踝关节休息。在14天治疗期间,每隔3天评估伤口大小(cm(2))、局部感染发生率、伤口床特征和疼痛水平(采用0-10儿科疼痛量表测量)的变化。结果:20名儿童(平均年龄5.6岁(+/- 1.33))被招募到研究中,并纳入分析。平均基线伤口面积为8.60 cm(2)(+/- 6.57)。伤口完全闭合的平均时间为12.95天(+/- 7.69),平均共4.70次访视(+/- 1.56)。平均VAS疼痛评分为9.55(+/- 0.69),而第14天为0.15(+/- 0.37)(p
Objective: To evaluate the clinical benefits, primarily tolerability and reduction in pain levels, associated with the use of a PHMB-impregnated biosynthetic cellulose dressing (Suprasorb X + PHMB) on paediatric heel lacerations.Method: These lacerations were caused when children, who were being transported on their parents' bicycles, got their heels trapped in the wheel spokes. Where these injuries just comprised skin contusion and laceration, treatment had previously comprised cleansing followed by application of conventional dressings and moist wound healing dressings. However, the high incidence of infection necessitated regular dressing changes, which caused parents and children stress and anxiety. This clinical evaluation assessed the benefits of a new treatment protocol, where the PHMB-impregnated biocellulose dressing was applied and left in situ until epithelialisation occurred. A cork splint was used for 3 days to prevent pes equinus and to let the ankle joint rest. Change in wound size (cm(2)), incidence of local infection, wound bed characteristics and pain levels (measured on a 0-10 paediatric pain scale) were assessed at 3-day intervals during the 14-day treatment period. Satisfaction with the dressing was also evaluated.Results: Twenty children (mean age 5.6 years (+/- 1.33) were recruited into the study and included in the analysis. The mean baseline wound area was 8.60cm(2) (+/- 6.57). The mean time to complete wound closure was 12.95 days (+/- 7.69) with a mean total of 4.70 visits (+/- 1.56). The mean VAS pain score was 9.55 (+/- 0.69), compared with 0.15 (+/- 0.37) on day 14 (p