Thin silicon strip detectors for beam monitoring in Micro-beam Radiation Therapy
Thin silicon strip detectors for beam monitoring in Micro-beam Radiation Therapy
复制标题
用于微束放射治疗中束流监测的薄硅条探测器
DOI：
10.1088/1748-0221/10/11/p11007
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发表时间：
2015
影响因子：
1.3
通讯作者：
B. Stugu
中科院分区：
文献类型：
--
作者：
M. Povoli;E. Alagoz;Alberto Bravin;I. Cornelius;E. Brauer;Pauline Fournier;Thor;A. Kok;M. Lerch;E. Monakhov;John Morse;M. Petasecca;H. Requardt;A. Rosenfeld;D. Røhrich;H. Sandaker;Murielle Salom'e;B. Stugu
微束放射治疗（MRT）是一种新兴的癌症治疗方法，目前正在法国格勒诺布尔的欧洲同步辐射设施（ESRF）开发。该技术使用高度准直和分割的X射线束阵列，具有极高的剂量率和非常小的发散度，以受益于剂量体积效应，从而保护健康组织。在任何光束异常和系统故障的情况下，必须安装特殊的安全措施，例如需要连续监测光束强度分布的紧急安全快门。在3DMiMic项目中，开发了一种新型硅条探测器，可以解决MRT的特殊功能，例如极高的空间分辨率和剂量率，作为安全快门系统的一部分。第一批原型已成功制造，并进行了旨在证明其适用于这种独特应用的实验。设计，制造和实验结果，以及任何确定的不足之处，为未来的优化报告和讨论在本文中。
Microbeam Radiation Therapy (MRT) is an emerging cancer treatment that is currently being developed at the European Synchrotron Radiation Facility (ESRF) in Grenoble, France. This technique uses a highly collimated and fractionated X-ray beam array with extremely high dose rate and very small divergence, to benefit from the dose-volume effect, thus sparing healthy tissue. In case of any beam anomalies and system malfunctions, special safety measures must be installed, such as an emergency safety shutter that requires continuous monitoring of the beam intensity profile. Within the 3DMiMic project, a novel silicon strip detector that can tackle the special features of MRT, such as the extremely high spatial resolution and dose rate, has been developed to be part of the safety shutter system. The first prototypes have been successfully fabricated, and experiments aimed to demonstrate their suitability for this unique application have been performed. Design, fabrication and the experimental results as well as any identified inadequacies for future optimisation are reported and discussed in this paper.