Cerebral angiogenesis and expression of angiogenic factors in aging rats after exercise
Cerebral angiogenesis and expression of angiogenic factors in aging rats after exercise
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DOI：
10.2174/156720206775541787
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发表时间：
2006-02-01
影响因子：
2.1
通讯作者：
Ding, Yuchuan
中科院分区：
文献类型：
--
作者：
Ding, Yun-Hong;Li, Jie;Ding, Yuchuan
运动对衰老大鼠油性血管生成的影响尚不清楚。我们启动这项研究的目的是为了确定运动是否可以诱导衰老大鼠以及先前报道的成年大鼠的血管生成。我们用来确定终点的标记物是血管内皮生长因子(VEGF)和血管生成素I和2，以及血管密度。老年(22月龄)雌性Fisher 344只大鼠(n=16)在跑步机上运动3周，每天30分钟，或作为非运动对照组。在练习方案结束时，显著(p
The effect that exercise has oil angiogenesis in the aging rat is-unknown. We initiated this study with the intent to determine if exercise could induce angiogenesis in aging rats, as well as in adult rats reported previously. The markers we used to determine our endpoint were vascular endothelial growth factor (VEGF) and angiopoietin I and 2, as well as vascular density. Aged (22 month old) female Fisher 344 rats (n=16) were exercised on a treadmill 30 minutes each day for 3 weeks, or housed as non-exercised controls for the same duration. At the end of the exercise protocol, a significant (p