Evaluation of a new Plasmodium lactate dehydrogenase assay (OptiMAL-IT®) for the detection of malaria
Evaluation of a new Plasmodium lactate dehydrogenase assay (OptiMAL-IT®) for the detection of malaria
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DOI：
10.1016/s0035-9203(03)80100-1
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发表时间：
2003-11-01
影响因子：
2.2
通讯作者：
Nosten, F.
中科院分区：
文献类型：
--
作者：
Pattanasin, S.;Proux, S.;Nosten, F.
2002年6月至7月，在泰国对271名无并发症疟疾患者进行了新的OptiMAL-IT（R）疟疾快速诊断测试。诊断恶性疟原虫的敏感性和特异性分别为88%和92%。对于恶性疟原虫以外的种属，敏感性为65%，特异性为99%。在低水平寄生虫血症时，新测试的性能明显下降。
The new OptiMAL-IT (R) rapid diagnostic test for malaria was evaluated in 271 patients in Thailand with uncomplicated malaria between June and July 2002. The sensitivity and specificity for the diagnosis of Plasmodium falciparum parasites were 88% and 92%, respectively. For species other than P. falciparum, the sensitivity was 65% and specificity was 99%. The performance of the new test decreased markedly at low levels of parasitaemia.