Associations between Infant and Parent Characteristics and Measures of Family Well-Being in Neonates with Seizures: A Cohort Study
Associations between Infant and Parent Characteristics and Measures of Family Well-Being in Neonates with Seizures: A Cohort Study
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DOI：
10.1016/j.jpeds.2020.02.024
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发表时间：
2020-06-01
影响因子：
5.1
通讯作者：
Glass, Hannah C.
中科院分区：
文献类型：
--
作者：
Franck, Linda S.;Shellhaas, Renee A.;Glass, Hannah C.
目的描述和确定危险因素的关键尺寸的幸福感在出院的家庭的新生儿急性症状性Seizure.Study设计这一前瞻性，观察性队列研究纳入了144个父母-婴儿二对新生儿急性症状性癫痫发作从9个儿科医院在新生儿癫痫登记。每个家庭的一位家长完成了出院调查，其中包括焦虑和抑郁的措施，健康相关的生活质量，对家庭的影响。多变量回归分析调整网站构建检查父母和婴儿的特征与wellbeing.Results在出院时，54%的父母报告的焦虑症状和32%的抑郁症状。缺氧缺血性脑病患儿的父母比其他癫痫病因患儿的父母更容易抑郁，生活质量更差。出院时婴儿年龄越大，父母的生活质量也越低。母亲受教育程度越高，对家庭的影响越大。所有这些差异均为中等至大的效应量，范围为0.52 ~ 0.78。结论新生儿癫痫患儿的父母普遍存在焦虑和抑郁症状，父母和婴儿的一些特征与父母的生活质量和家庭幸福感有关。这些发现呼吁采取行动，改善新生儿癫痫发作婴儿父母的心理健康筛查和服务。
Objective To characterize and determine risk factors for key dimensions of well-being at hospital discharge in families of neonates with acute symptomatic seizures.Study design This prospective, observational cohort study enrolled 144 parent-infant dyads among neonates with acute symptomatic seizures from 9 pediatric hospitals in the Neonatal Seizure Registry. One parent per family completed a discharge survey, which included measures of anxiety and depression, health-related quality of life, and impact on the family. Multivariable regression analyses adjusted for site were constructed to examine parent and infant characteristics associated with well-being.Results At discharge, 54% of parents reported symptoms of anxiety and 32% reported symptoms of depression. Parents of infants with hypoxic-ischemic encephalopathy reported more depression and worse quality of life than parents of infants with other seizure etiologies. Parental quality of life was also lower with greater infant age at discharge. A higher level of maternal education was associated with greater impact on the family. All these differences were medium to large effect sizes, ranging from 0.52 to 0.78.Conclusions Symptoms of anxiety and depression are common in parents of infants with neonatal seizures, and several parent and infant characteristics are associated with poorer parental quality of life and family well-being. These findings are a call to action to improve mental health screening and services for parents of infants with neonatal seizures.