Adsorption and desorption behaviors of cetylpyridinium chloride on hydroxyapatite nanoparticles with different morphologies.
Adsorption and desorption behaviors of cetylpyridinium chloride on hydroxyapatite nanoparticles with different morphologies.
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DOI：
10.4012/dmj.2015-420
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发表时间：
2016-07
影响因子：
2.5
通讯作者：
M. Okada;Daisuke Hiramatsu;T. Okihara;T. Matsumoto
中科院分区：
文献类型：
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作者：
M. Okada;Daisuke Hiramatsu;T. Okihara;T. Matsumoto
应用羟基磷灰石纳米颗粒修复牙釉质损伤已引起人们的关注。在这项研究中，具有不同的形貌（球形，短棒，长棒和纤维形态）的HAp纳米粒子通过化学沉淀法合成没有添加模板分子，和阳离子抗菌剂，氯化十六烷基吡啶（CPC）的吸附/脱附行为的HAp纳米粒子进行了评价。CPC在HAp纳米颗粒上的吸附均表现为Langmuir型吸附，短棒/长棒HAp纳米颗粒比球形/纤维状HAp纳米颗粒对CPC的吸附更稳定。CPC从短棒/长棒HAp纳米颗粒上的脱附速率比球形/纤维状HAp纳米颗粒慢。具有不同CPC释放曲线的HAp纳米颗粒具有潜在的应用前景，可作为具有抗菌性能的纳米颗粒牙釉质修复剂。
Application of hydroxyapatite (HAp) nanoparticles to repair damaged enamel has attracted recent attention. In this study, HAp nanoparticles with various morphologies (spherical, short-rod, long-rod and fiber morphologies) were synthesized via chemical precipitation methods without the addition of template molecules, and the adsorption/desorption behaviors of a cationic antibacterial agent, cetylpyridinium chloride (CPC), on the HAp nanoparticles were evaluated. The adsorption of CPC on each HAp nanoparticle showed Langmuir-type adsorption, and the short-rod/long-rod HAp nanoparticles showed thermodynamically more stable adsorption of CPC than that with the spherical/fiber HAp nanoparticles. The desorption rate of CPC from the short-rod/long-rod HAp nanoparticles was slower than that of the spherical/fiber HAp nanoparticles. The HAp nanoparticles with different CPC release profiles presented here have potential applications as nanoparticulate enamel repair agents with antibacterial properties.