Prenatal development of the rat dorsal root ganglia
Prenatal development of the rat dorsal root ganglia
复制标题
大鼠背根神经节的产前发育
作者：
S. Matsuda;Y. Uehara
本研究描述了在通过胰蛋白酶消化和HCl水解去除细胞外结缔组织成分后，使用扫描电子显微镜在产前大鼠背根神经节中神经母细胞的发育和假单极化以及卫星细胞的成熟的三维方面。在妊娠14天时，绝大多数神经元是梭形或双极的，只有3%是单极的，而在16天和18天时，这一百分比分别增加到30%和91%。中枢和外周神经元突起的起始部分逐渐彼此接近并形成共同的起始部分。最后，这一共同起始部分的细胞质变薄并伸长形成成熟细胞的茎突。卫星细胞从研究时期开始就存在，但复杂的分支卫星细胞突起网络仅在约17天后发育。
SummaryThis study describes three-dimensional aspects of the development and pseudo-unipolarization of neuroblasts and the maturation of satellite cells in prenatal rat dorsal root ganglia, using scanning electron microscopy, after removal of extracellular connective tissue components by trypsin digestion and HC1 hydrolysis.At 14 days of gestation, the vast majority of neurons are spindle-shaped or bipolar and only 3% are unipolar, while at 16 and 18 days this percentage has increased to 30% and 91%, respectively. The initial portions of the central and peripheral neuronal processes gradually approach each other and form a common initial portion. Finally, the cytoplasm of this common initial portion becomes thinner and elongates to form the stem process of the mature cell.Satellite cells are present from the beginning of the period studied, but intricate networks of branching satellite cell processes only develop after about day 17.