Estimating the delay of the fMRI response

Estimating the delay of the fMRI response
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DOI:
10.1006/nimg.2002.1096
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发表时间:
2002-07-01
期刊:
影响因子:
5.7
通讯作者:
Evans, AC
Evans, AC
中科院分区:
医学1区
文献类型:
--
作者:
Liao, CH;Worsley, KJ;Evans, AC

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我们提出了一种快速,高效,通用,简单,有效,和强大的方法估计和推理的延迟的fMRI响应建模为时间转移的血流动力学响应函数(HRF)。我们估计的移位无偏使用两个最佳选择的基函数的频谱的时移HRF。这在每个体素处完成,以创建估计延迟及其标准偏差的图像。这可以用于比较不同体素处的相同刺激或相同体素处的不同刺激的延迟。我们的方法相比,其他替代品和验证的fMRI数据集从疼痛感知的实验。(C)2002 Elsevier Science(美国)。
We propose a fast, efficient, general, simple, valid, and robust method of estimating and making inference about the delay of the fMRI response modeled as a temporal shift of the hemodynamic response function (HRF). We estimate the shift unbiasedly using two optimally chosen basis functions for a spectrum of time shifted HRFs. This is done at every voxel, to create an image of estimated delays and their standard deviations. This can be used to compare delays for the same stimulus at different voxels, or for different, stimuli at the same voxel. Our method is compared to other alternatives and validated on an fMRI data set from an experiment in pain perception. (C) 2002 Elsevier Science (USA).