Immunotherapy for recalcitrant warts in children using intralesional mumps or Candida antigens
Immunotherapy for recalcitrant warts in children using intralesional mumps or Candida antigens
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DOI：
10.1046/j.1525-1470.2003.20318.x
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发表时间：
2003-05-01
影响因子：
1.5
通讯作者：
Horn, TD
中科院分区：
文献类型：
--
作者：
Clifton, MM;Johnson, SM;Horn, TD
病灶内注射腮腺炎和念珠菌皮试抗原已被证明可有效治疗疣。儿童疣通常很难治疗。为了确定病灶内皮试抗原注射治疗儿童耐药疣的疗效，我们对 47 名患有一处或多处疣的儿童患者进行了病灶内注射腮腺炎或念珠菌皮试抗原至一处疣的治疗。 22 名耐药疣患者 (47%) 的治疗疣完全消退。平均需要 3.78 次治疗。另外 34% 的儿童的疣改善超过 25%。 68% 患有超过 1 个疣的受试者还注意到，远处未经治疗的疣至少部分消退（大于 25% 消退），其中 34% 的受试者完全消退。我们的结论是，病灶内注射皮试抗原对于患有顽固性非生殖器皮肤疣的儿童来说是一种有效的治疗方法。
Intralesional injection of mumps and Candida skin test antigens has been shown to be effective in the treatment of warts. Warts are generally difficult to treat in children. To determine the efficacy of intralesional skin test antigen injection for the treatment of resistant warts in children, we treated 47 pediatric patients with one or more warts with intralesional injection of mumps or Candida skin test antigen into one wart. Twenty-two patients (47%) with resistant warts experienced complete resolution of treated warts. An average of 3.78 treatments were necessary. An additional 34% of children had a greater than 25% improvement in their warts. Sixty-eight percent of subjects with more than one wart also noted at least partial resolution (greater than 25% resolution) of untreated warts at distant sites, with 34% experiencing complete resolution. We concluded that intralesional injection of skin test antigens is an effective therapy for children who have recalcitrant, nongenital, cutaneous warts.