Rapid recontamination with MRSA of the environment of an intensive care unit after decontamination with hydrogen peroxide vapour
Rapid recontamination with MRSA of the environment of an intensive care unit after decontamination with hydrogen peroxide vapour
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DOI：
10.1016/j.jhin.2007.05.009
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发表时间：
2007-08-01
影响因子：
6.9
通讯作者：
Hawkey, P. M.
中科院分区：
文献类型：
--
作者：
Hardy, K. J.;Gossain, S.;Hawkey, P. M.
耐甲氧西林金黄色葡萄球菌（MRSA）在医院环境中持续存在，常规清洁程序不一定能消除污染。在重症监护室进行了一项前瞻性研究，以确定MRSA的环境污染水平，评估过氧化氢蒸汽（HPV）去污的有效性，并确定环境再污染率。在使用HPV前的三个月内，从11.2%的环境站点中分离出MRSA，流行病学分型显示环境中循环的类型与定植患者相似。在患者出院和使用常规方法进行终端清洁后，从5个部位（17.2%）分离出MRSA。在HPV净化后但在患者再入院前，MRSA未从环境中分离出来。24小时后再入院的病人，包括两个与MRSA定殖，从五个网站分离的有机体。这些菌株与患者定植的菌株无法区分，但并不都局限于定植患者的紧邻区域。在使用HPV后的8周内，每周对环境进行采样，从16.3%的地点分离出MRSA。过氧化氢蒸汽可以有效地消除环境中的细菌，但再污染的快速速率表明，它不是在开放式重症监护病房中保持低水平环境污染的有效手段。(c)2007年，医院感染协会。由爱思唯尔有限公司出版。保留所有权利。
Meticillin-resistant Staphylococcus aureus (MRSA) persists in the hospital environment and conventional cleaning procedures do not necessarily eliminate contamination. A prospective study was conducted on an intensive care unit to establish the level of environmental contamination with MRSA, assess the effectiveness of hydrogen peroxide vapour (HPV) decontamination and determine the rate of environmental recontamination. MRSA was isolated from 11.2% of environmental, sites in the three months preceding the use of HPV and epidemiotogical typing revealed that the types circulating within the environment were similar to those colonising patients. After patient discharge and terminal cleaning using conventional methods, MRSA was isolated from five sites (17.2%). After HPV decontamination but before the readmission of patients, MRSA was not isotated from the environment. Twenty-four hours after readmitting patients, including two colonized with MRSA, the organism was isotated from five sites. The strains were indistinguishable from a strain with which a patient was colonized but were not all confined to the immediate vicinity of the colonized patient. In the eight weeks after the use of HPV, the environment was sampled on a weekly basis and MRSA was isolated from 16.3% sites. Hydrogen peroxide vapour is effective in eliminating bacteria from the environment but the rapid rate of recontamination suggests that it is not an effective means of maintaining low levels of environmental contamination in an open-plan intensive care unit. (c) 2007 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved.