Corpus callosum size in autism
Corpus callosum size in autism
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DOI：
10.1212/wnl.55.7.1033
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发表时间：
2000-10-10
期刊：
影响因子：
9.9
通讯作者：
Keshavan, MS
中科院分区：
文献类型：
--
作者：
Hardan, AY;Minshew, NJ;Keshavan, MS
对22名非智力落后的自闭症受试者和22名单独匹配的对照组进行了MRI扫描，测量了胼胝体的7个亚区的大小。自闭症组前亚区面积较小。在一个子样本中，对颅内、总脑和白质体积的测量进行了调整，组之间的差异仍然显著。其他亚区均未发现差异。这一观察结果与自闭症患者额叶功能障碍的报道是一致的。
The size of the seven subregions of the corpus callosum was measured on MRI scans from 22 non-mentally retarded autistic subjects and 22 individually matched controls. Areas of the anterior subregions were smaller in the autistic group. In a subsample, measurements were adjusted for intracranial, total brain, and white matter volumes and the differences between groups remained significant. No differences were found in the other subregions. This observation is consistent with the frontal lobe dysfunction reported in autism.