Toward Coordinate-based Cognition Dictionaries: A BrainMap and Neurosynth Demo.
Toward Coordinate-based Cognition Dictionaries: A BrainMap and Neurosynth Demo.
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走向基于坐标的认知词典：BrainMap 和 Neurosynth 演示。
DOI：
10.1016/j.neuroscience.2022.02.016
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发表时间：
2022
期刊：
影响因子：
3.3
通讯作者：
Zang,Yu-Feng
中科院分区：
文献类型：
--
作者：
Lu,Qiu-Yu;Towne,JonathanM;Lock,Matthew;Jiang,Chao;Cheng,Zhi-Xiang;Habes,Mohamad;Zuo,Xi-Nian;Zang,Yu-Feng
长期以来，描述特定大脑区域的功能参与一直是认知神经科学的核心挑战。功能性磁共振成像（fMRI）技术为映射功能性神经网络提供了解决方案。结构-功能对应的复杂性使得精心设计的任务很难完全捕捉高阶认知功能。其他研究实践，如脑行为关联或组间比较，因此被广泛用于探索特定大脑区域的认知相关性。然而，在出版物中，解释来自特定大脑区域的结果与其潜在的认知功能过于笼统。在这里，我们使用两个例子，即，一项脑智能相关性研究和一项抑郁对照比较元研究，以证明两个神经成像在线数据库BrainMap和Neurosynth的使用。这两个数据库的一个关键用途是收集大量基于认知任务的功能磁共振成像（tb-fMRI）研究的结果，即，标准大脑空间的坐标。就像查找“基于坐标的认知词典”一样，研究人员可以接收大量相关的tb-fMRI激活信息，其特征在于认知领域、特定认知功能、认知任务范式和相关出版物。令人惊讶的是，我们发现只有不到1%的大脑行为关联或组间比较研究使用了这种字典方法。我们鼓励社区进一步参与现有的数据库，对神经成像进行具体和全面的解释，并指导未来的实验tb-fMRI设计。
Characterizing the functional involvement of specific brain regions has long been a central challenge in cognitive neuroscience. Functional magnetic resonance imaging (fMRI) techniques have offered solutions for mapping functional neural networks. The complex nature of structure-function correspondence makes an elaborate task design difficult to fully capture higher-order cognitive function. Other research practices, such as brain-behavior association or between-group comparisons, are thus widely used to explore cognitive correlations with specific brain regions. However, interpreting the results derived from a specific brain region with their underlying cognitive functions has been too general in publications. Here, we use two examples, i.e., a brain-intelligence correlation study and a depression-control comparison meta-study, to demonstrate use of two neuroimaging online databases, BrainMap and Neurosynth. One key utility of the two databases is collecting results from massive cognitive task-based fMRI (tb-fMRI) studies, i.e., coordinates in standard brain space. Just like looking up a “coordinate-based cognition dictionary”, researchers can receive a plethora of related tb-fMRI activation information characterized by cognitive domains, specific cognitive functions, cognitive task paradigms, and related publications. Surprisingly, we found that only less than 1% of brain-behavior association or between-group comparison studies have utilized this dictionary approach. We encourage the community to further engage with the existing databases for specific and comprehensive interpretation of neuroimaging as well as guidance of future experimental tb-fMRI design.