A New Microcontroller-Based Human Brain Hypothermia System
A New Microcontroller-Based Human Brain Hypothermia System
复制标题
一种新型基于微控制器的人脑低温系统
DOI：
10.1007/s10916-005-6107-2
复制
发表时间：
2005
影响因子：
5.3
通讯作者：
I. Güler
中科院分区：
文献类型：
--
作者：
Metin Kapıdere;R. Ahiska;I. Güler
许多研究表明，在麻醉状态下对大脑进行人工低温，将直肠温度降至33°C，可以产生明显的预防作用，保护大脑免受缺氧。目前临床实践中采用的减少脑组织耗氧量的方法中，最有效的是颅脑低温疗法（CCH）。它在心血管外科、神经外科、神经肾病学和许多其他医疗实践领域得到了更广泛的应用。在本研究中，设计并构建了一种基于微控制器的人脑低温系统（HBHS）。该系统旨在冷却和加热大脑。 HBHS由热电低温头盔、控制装置和动力装置组成。头盔温度由 8 位 PIC16F877 微控制器控制，该微控制器使用 MPLAB 编辑器进行编程。温度被转换为 10 位数字，并由已输入微控制器的预设值自动控制。控制校准并测试工作范围。通过微控制器将头盔温度控制在-5至+46∘C之间，精度为±0.5∘C。
Many studies show that artificial hypothermia of brain in conditions of anesthesia with the rectal temperature lowered down to 33∘C produces pronounced prophylactic effect protecting the brain from anoxia. Out of the methods employed now in clinical practice for reducing the oxygen consumption by the cerebral tissue, the most efficacious is craniocerebral hypothermia (CCH). It is finding even more extensive application in cardiovascular surgery, neurosurgery, neurorenimatology and many other fields of medical practice. In this study, a microcontroller-based designed human brain hypothermia system (HBHS) is designed and constructed. The system is intended for cooling and heating the brain. HBHS consists of a thermoelectric hypothermic helmet, a control and a power unit. Helmet temperature is controlled by 8-bit PIC16F877 microcontroller which is programmed using MPLAB editor. Temperature is converted to 10-bit digital and is controlled automatically by the preset values which have been already entered in the microcontroller. Calibration is controlled and the working range is tested. Temperature of helmet is controlled between −5 and +46∘C by microcontroller, with the accuracy of ± 0.5∘C.