Infection and the risk of spontaneous cervical artery dissection - A case-control study
Infection and the risk of spontaneous cervical artery dissection - A case-control study
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DOI：
10.1161/01.str.0000078309.56307.5c
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发表时间：
2003-07-01
期刊：
影响因子：
8.3
通讯作者：
Tzourio, C
中科院分区：
文献类型：
--
作者：
Guillon, B;Berthet, K;Tzourio, C
背景和目的：自发性颈动脉夹层（SCAD）的发生可能与一些体质和环境危险因素有关。这项工作探讨了最近的感染和SCAD之间的关联在医院为基础的病例对照study.Methods-Forty-7例SCAD和52例缺血性卒中从另一个原因前瞻性和连续招募2个神经科。一个专门设计的问卷被用来评估历史的急性感染，可能发生在一个月内血管events.Results-Acute感染更频繁的SCAD患者（31.9%）比对照组（13.5%）（粗比值比，3.0; 95%置信区间，1.1至8.2; P=0.032）。这种关联是更强的患者多（比值比，6.4）比单动脉（比值比，2.1）dispensation. Conclusions近期感染是一个危险因素，可能是一个触发SCAD。
Background and Purpose-Several constitutional and environmental risk factors may be involved in the occurrence of spontaneous cervical artery dissection (SCAD). This work explored the association between recent infection and SCAD in an hospital-based case-control study.Methods-Forty-seven patients with SCAD and 52 with ischemic stroke from another cause were prospectively and consecutively recruited by 2 neurology departments. A specially designed questionnaire was used to assess the history of an acute infection that could have occurred within a month before the vascular event.Results-Acute infection was more frequent in patients with SCAD (31.9%) than in control subjects (13.5%) (crude odds ratio, 3.0; 95% confidence interval, 1.1 to 8.2; P=0.032). This association was stronger in patients with multiple (odds ratio, 6.4) than single artery (odds ratio, 2.1) dissection.Conclusions-Recent infection is a risk factor and could be a trigger for SCAD.