Measurement and assessment of study quality and reporting quality
Measurement and assessment of study quality and reporting quality
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DOI：
10.1016/j.zefq.2014.09.022
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发表时间：
2014-01-01
影响因子：
1.1
通讯作者：
Meerpohl, Joerg J.
中科院分区：
文献类型：
--
作者：
Bluemle, Anette;von Elm, Erik;Meerpohl, Joerg J.
进行临床试验是为了评估临床干预措施的有效性和安全性，或调查其他未明确的（如诊断）研究问题。但并不是每一项临床研究都得到了最佳的计划、执行和分析，因此面临着可能扭曲（偏差）研究结果的系统性错误的风险。临床研究应按照特定的质量标准进行，以减少这些风险。为了评估研究的方法学质量，开发了Cochrane偏倚风险工具等工具。但只能根据报道来评价。通常，研究文章中缺少关于研究行为和分析的重要信息，并且在大多数情况下，详细的研究方案不是免费提供的。适用于不同研究类型的报告指南有助于提高临床研究报告的透明度和完整性，从而提高报告质量。
Clinical trials are undertaken to evaluate the effectiveness and safety of clinical interventions or to investigate other unclarified (e.g. diagnostic) research questions. But not every clinical study is optimally planned, conducted and analysed and is therefore exposed to risk of systematic errors which can distort (bias) the study results. Clinical studies should be conducted in accordance with specific quality criteria in order to reduce these risks. To estimate the methodological quality of studies instruments such as the Cochrane Risk of Bias tool were developed. But it can only be appraised what is reported. Often important information on the conduct and analysis of a study is missing in research articles, and in most cases detailed study protocols are not freely available. Reporting guidelines available for different study types can help improve the transparency and completeness of reports of clinical studies and thus the reporting quality.