Development of ischemic colitis and scleroderma renal crisis following methylprednisolone pulse therapy for progressive systemic sclerosis.
Development of ischemic colitis and scleroderma renal crisis following methylprednisolone pulse therapy for progressive systemic sclerosis.
复制标题
甲基强的松龙冲击治疗进行性系统性硬化症后出现缺血性结肠炎和硬皮病肾危象。
DOI：
10.2169/internalmedicine.35.583
复制
发表时间：
1996
影响因子：
1.2
通讯作者：
M. Yamakido
中科院分区：
文献类型：
--
作者：
Y. Yamanishi;S. Yamana;S. Ishioka;M. Yamakido
我们描述了一位进行性系统性硬化症患者，他在激素冲击治疗后出现了缺血性结肠炎和硬皮病肾危象。对缺血性结肠炎和硬皮病肾危象发生的可能机制进行了讨论。我们的结论是，对于进行性系统性硬化症患者，应谨慎使用大剂量的类固醇，特别是通过类固醇脉冲治疗。
We describe a patient with progressive systemic sclerosis who developed ischemic colitis and scleroderma renal crisis following steroid pulse therapy. The possible pathogenic mechanisms of ischemic colitis and scleroderma renal crisis development are discussed. We conclude that the administration of steroids in high doses, especially via steroid pulse therapy, should be undertaken with caution for progressive systemic sclerosis patients.