A fast magnetic resonance imaging technique for children with mediastinal lymphoma: Work in progress

A fast magnetic resonance imaging technique for children with mediastinal lymphoma: Work in progress
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DOI:
10.1002/mpo.1247
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发表时间:
2001-12-01
期刊:
MEDICAL AND PEDIATRIC ONCOLOGY
影响因子:
--
通讯作者:
Rupprecht, T
Rupprecht, T
中科院分区:
其他
文献类型:
--
作者:
Wagner, M;Kuth, R;Rupprecht, T

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背景。纵隔淋巴瘤在诊断时通常表现为一个大肿瘤。通常胸部x线摄影是第一成像方式,用于疾病过程中的常规随访。我们中心开发了一种新的快速核磁共振成像技术作为替代方案。在一项初步研究中,三名纵隔淋巴瘤患者的结果是有希望的。过程。诊断后,上述患者在0.2 T低场磁共振扫描仪上进行进一步检查,采用改良的真FISP序列(见文本),采集时间为3.6-4.6秒。随访包括x线摄影和MRI。确诊后再次行x线摄影和MRI随访,1例2次,1例3次,1例5次。图像由两名儿科放射科医生评估和比较。结果。x线摄影和MRI的总检查时间相当。在9张影像中,有7张的MRI影像更清楚地显示了肿瘤,并提供了关于肿瘤结构和定位的额外信息,以及伴随的问题,如心包积液。结论。在纵隔淋巴瘤的诊断和随访中,真正的FISP MRI可能被证明是一个很好的替代x线摄影。(C) 2001 Wiley-Liss, inc。
Background. Mediastinal lymphoma often presents as a large tumor at the time of diagnosis. Usually chest X-ray filming is the first imaging modality and it is used for routine follow-up during the course of the disease. A new and very fast MRI technique has been developed at our center as an alternative. Results in three patients with mediastinal lymphoma during a pilot study are promising. Procedure. After diagnosis the above patients were additionally investigated in a 0.2 T lowfield MR-scanner by a modified true FISP sequence (see text) with an acquisition time of 3.6-4.6 sec. Follow-up was performed by both, X-ray filming and MRI. After diagnosis the patients, again, had both X-ray filming and MRI investigation for follow-up: one patient 2, one patient 3, and one patient 5 times. Images were evaluated and compared by two pediatric radiologists. Results. Total investigation times for radiography and MRI were comparable. The tumor was better visualized by MRI on seven of nine images and gave additional information about the structure and the localization of the tumor as well as concomitant problems such as pericardial effusion. Conclusion. True FISP MRI may prove to be a good alternative to X-ray filming in the diagnosis and follow-up of mediastinal lymphoma. (C) 2001 Wiley-Liss, inc.