NUCLEAR MAGNETIC-RESONANCE IMAGING OF THE LIVER - INITIAL EXPERIENCE
NUCLEAR MAGNETIC-RESONANCE IMAGING OF THE LIVER - INITIAL EXPERIENCE
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DOI：
10.2214/ajr.138.2.193
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发表时间：
1982-01-01
影响因子：
5
通讯作者：
GILDERDALE, DJ
中科院分区：
文献类型：
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作者：
DOYLE, FH;PENNOCK, JM;GILDERDALE, DJ
用全身核磁共振仪对12名正常志愿者和32名患者进行了肝脏核磁共振扫描，并与X线计算机断层扫描（CT）结果进行了比较。进行两种类型的NMR扫描，饱和恢复和反转恢复，以获得自旋-晶格弛豫时间T1的值。虽然饱和恢复扫描显示软组织细节很少，但反转恢复扫描显示了叶间裂、肝静脉、门静脉、胆管和胆囊。与CT相比，这两种类型的NMR扫描显示出由于呼吸运动而导致的一些模糊，但从胃中的气液界面穿过肝脏的线性伪影要少得多。CT和NMR均证实了肝脏内的局灶性病变，尽管仅通过NMR识别了一个局灶性萎缩区域和另一个肝梗死区域。在弥漫性疾病中，模式各不相同。对于脂肪变性，CT几乎可以诊断，而核磁共振没有显示任何特定特征。在血色素沉着症、肝炎、8例肝硬化和1例威尔逊病中，两种技术均显示不同特异性的异常。2例肝硬化和1例原发性胆汁性肝硬化仅核磁共振扫描异常。核磁共振图像在解剖学上已经足够详细，可以与技术先进的CT进行认真的比较。揭示的信息是根本不同的，可以预期有一些诊断效用。
NMR scans of the liver were obtained in 12 normal volunteers and 32 patients using a whole-body machine and the results were compared with x-ray computed tomography (CT). Two types of NMR scan, saturation-recovery and inversion-recovery, were performed in order to obtain values for the spin-lattice relaxation time, T1. Although the saturation-recovery scans show little soft-tissue detail, the inversion-recovery scans demonstrated the interlobar fissure, hepatic veins, portal veins, bile ducts and gallbladder. In comparison with CT, both types of NMR scan showed some blurring due to respiratory movement but much less linear artifact across the liver from the air-fluid interface in the stomach. Focal disesae within the liver was demonstrated by both CT and NMR, although an area of focal atrophy and another of hepatic infarction were only recognized with NMR. In diffuse disease the pattern varied. In steatosis CT was virtually diagnostic, while NMR showed no specific features. In hemochromatosis, hepatitis, 8 cases of cirrhosis and 1 of Wilson''s disease, both techniques showed abnormalities of varying specificity. In 2 cases of cirrhosis and 1 of primary biliary cirrhosis, only the NMR scan was abnormal. NMR images are now sufficiently anatomically detailed to permit serious comparisons with technically advanced CT. The information revealed is fundamentally different and can be expected to have some diagnostic utility.