Sequencing of exons 16 and 17 of the beta-amyloid precursor protein gene reveals the beta-amyloid sequence to be normal in cases of the parkinson dementia complex of Guam.
Sequencing of exons 16 and 17 of the beta-amyloid precursor protein gene reveals the beta-amyloid sequence to be normal in cases of the parkinson dementia complex of Guam.
复制标题
β-淀粉样蛋白前体蛋白基因的外显子 16 和 17 的测序显示，关岛帕金森痴呆症患者的 β-淀粉样蛋白序列正常。
DOI：
10.1007/bf02260915
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
Hardy,J
中科院分区：
文献类型：
--
作者：
Harlin,MC;Crawford,F;Perl,DP;Steele,J;Hardy,J
Exons 16 and 17 of the β-amyloid precursor protein gene has been sequenced in individuals with the amyotropic lateral sclerosis/Parkinson's dementia complex of Guam to test the hypothesis that this disease is an allelic variant of Alzheimer's disease and to test whether sequence differences within β-amyloid in this population contributes to the non-deposition of this peptide in the disorder. The sequence was normal.
