Channels: Rotamers affect ion conductance.
Channels: Rotamers affect ion conductance.
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通道:旋转异构体影响离子电导。
DOI:
10.1038/nchembio.1115
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发表时间:
2012
影响因子:
14.8
通讯作者:
Akabas,MylesH
中科院分区:
文献类型:
--
作者:
Akabas,MylesH
A major determinant of the ion flux rate through acetylcholine receptors is a ring of five residues, four glutamates and a glutamine, at the channel's cytoplasmic mouth. The glutamates adopt alternate rotamer conformations so that only two directly affect channel conductance.