Local cerebral glucose utilization in the homozygous Brattleboro rat.
Local cerebral glucose utilization in the homozygous Brattleboro rat.
复制标题
纯合布拉特尔伯勒大鼠的局部脑葡萄糖利用。
DOI：
10.1016/0304-3940(85)90159-4
复制
发表时间：
1985
影响因子：
2.5
通讯作者：
Crosby,G
中科院分区：
文献类型：
--
作者：
Schwartz,WJ;Crosby,G
[14C]脱氧葡萄糖技术被用来测量纯合子雄性Brattleboro和年龄匹配的Long-Evans对照组大鼠的脑葡萄糖利用。与对照组相比，Brattleboro纯合子组的每日水分摄入量和血浆渗透压显著增加，体重显著降低。两种菌株对整个大脑和46个不同大脑结构的葡萄糖利用没有显著差异。我们的结果表明，加压素不是维持静息、清醒大鼠整体脑葡萄糖利用所必需的。
The [14C]deoxyglucose technique was used to measure brain glucose utilization in homozygous male Brattleboro and age-matched Long-Evans control rats. Brattleboro homozygotes had significantly higher daily water intakes and plasma osmolalities and significantly lower body weights than controls. Glucose utilization for the brain as a whole and for 46 discrete brain structures was not significantly different for the two strains. Our results indicate that vasopressin is not essential for the maintenance of overall brain glucose utilization in resting, awake rats.